Mostrando entradas con la etiqueta Autismo. Mostrar todas las entradas
Mostrando entradas con la etiqueta Autismo. Mostrar todas las entradas

lunes, mayo 26, 2014

Mice With Mohawks Yield Clues to Autism

NBC News.com
It's not every day you see a mouse with a mohawk. But that's what researchers saw while studying mice that had a genetic mutation linked to autism.
The mohawks that the mice were sporting actually resulted from their "over-grooming" behavior, repeatedly licking each other's hair in the same direction.
The behavior resembles the repetitive motions displayed by some people with autism, and the researchers say their experiments reveal a link between the genetic causes of autism and their effects on the brain, suggesting potential avenues for treating the disorder.
Image: Mouse with mohawk  
Nature via Live Science
Mice that have a genetic mutation linked to autism groom their hair into mohawk-like hairstyles.
"Our study tells us that to design better tools for treating a disease like autism, you have to get to the underlying genetic roots of its dysfunctional behaviors, whether it is over-grooming in mice or repetitive motor behaviors in humans," study researcher Gordon Fishell, a neuroscientist at NYU Langone Medical Center, said in a statement.
Autism is a spectrum of developmental disorders that involve social impairments and communication deficits. People with autism may also engage in repetitive behaviors, such as rocking or hand flapping. [ Beyond Vaccines: 5 Things That Might Really Cause Autism ]
In the study, detailed today (May 25) in the journal Nature, the researchers bred mice that lacked a gene for a protein called Cntnap4, which is found in brain cells called interneurons.
Having low levels of this protein leads to the abnormal release of two brain-signaling molecules, known as dopamine and GABA. Dopamine is involved in sensations of pleasure; GABA (which stands for gamma-aminobutyric acid) dampens neural activity and regulates muscle tone.
Mice that lacked the gene for this critical brain protein were found to obsessively groom their fellow animals' fur into mohawk-like styles, suggesting a link between genetics, brain function and autistic behaviors.
"There have been many candidate genes implicated in contributing to autism, but animal and human studies to identify their action have so far not led to any therapies," Fishell said in the statement. "Our research suggests that reversing the disease's effects in signaling pathways like GABA and dopamine are potential treatment options," he said.
— Tanya Lewis, LiveScience

martes, abril 02, 2013

The waitress, the autistic girl and the broken hamburger

Last Sunday was just an average morning for Anna Kaye MacLean. Her sister, 7-year-old Arianna, had slept over at her house the night before and seemed to have woken up in a good mood - which is not always a given for a child with autism.
After determining that Arianna’s mood was stable enough for a day of fun activities outside the home, MacLean and her husband decided to take Arianna out to lunch, with a bonus visit to the Easter Bunny afterward. They decided to eat lunch at the Chili’s Bar and Grill in Midvale, Utah, where a beautiful thing happened - and went viral.
MacLean requested a booth facing the window, knowing it would allow her sister the freedom to move around, while also keeping her entertained by watching what was going on outside. The hostess happily obliged and said their server would be over to greet them soon. The MacLean party was going to be one of Lauren Wells' last tables of the day, and with a bright smile, she approached the party to introduce herself and take drink orders.
Before she could even say, “Hi, welcome to Chili’s, I’m Lauren and I’ll be your waitress,” Arianna had excitedly rattled off her entire order: chocolate milk, a cheeseburger with pickles and a side of fries.
Wells delivered the food shortly, but as MacLean watched Arianna devour her French fries, she noticed that her sister wasn’t touching her cheeseburger.
“It was really, really bizarre,” MacLean told CNN in a phone interview. “Arianna loves anything in a hamburger bun. She’s obsessed with hamburgers or ‘Krabby Patties,’” an ode to one of Arianna’s favorite cartoon shows, Spongebob Squarepants.
MacLean asked her sister if she was going to eat her cheeseburger. “No, I don’t want it,” Arianna responded. “It’s broked. I need a new one that’s fixed.”
It’s a standard Chili’s policy to cut a child’s burger in half to ensure the meat is fully cooked to 170° degrees, and that's what was "broken."
When Wells returned to the table, she noticed Arianna was crying, and asked what was the matter.
"I know this is going to sound silly, but I need to order another cheeseburger," MacLean told the server. Wells had a concerned look on her face and MacLean was quick to assure her that there was nothing wrong with the food. "No, no, no, this one is fine," she explained, "But it’s cut in half and she thinks it's broke.'” 
MacLean quietly told Wells about Arianna’s autism and adamantly said she wanted to pay for the additional burger. But instead of speaking to MacLean, Wells leaned over to the little girl and addressed her directly, saying, “Ohmygosh! I brought you a broken cheeseburger! I’ll go get you a new one.”
Arianna stopped crying shortly after. MacLean, particularly moved by this, said Wells' exchange with her sister was something she had never experienced before.
“I think most people, just out of fear and the unknown, don’t know how to interact with a kid with autism, so people will usually just keep the interaction with me.” When necessary, MacLean explains her sister's condition.
Wells graduated from the University of Utah in May 2012 with a degree in psychology and hopes to do social work with children in the future. She also has an autistic family member, and said that while she thought Arianna might be autistic, she never assumes anything.
“I treated her the same way that [I would] any other kid who would be crying, but in her case, it was something different,” said Wells. She approached her manager Brad Cattermole, who told her they would happily switch out the broken burger for a new one.
Cattermole, too, stopped by the table and knelt down to speak with Arianna at eye level to apologize again. “You know, I heard we brought you a broken cheeseburger and I am so sorry. We’re back there making you a new one, but let me bring you out some french fries while you’re waiting.”
MacLean says one of the main reasons the exchange was so special was Wells' and Cattermole's decision to speak to Arianna directly.
“It was so cool because it was so intimate. [Brad] wasn’t trying to be loud or trying to make his presence know to anybody else. It was just very, very private, very intimate,” said MacLean.
“Our goal is to make guests feel special, so anything we can do to make an experience over the top of special, we give our servers the power to make the decisions to make that happen,” said Cattermole in a phone interview with CNN. “We’re trying to get each server to connect to each table individually and Lauren is amazing at connecting with our guests.”
MacLean noticed that, surprisingly, Arianna wasn’t upset about the cheeseburger. In fact, she was uncharacteristically calm about the entire situation.
“This was so bizarre because usually, that would have just led to a huge meltdown,” MacLean said, adding that a typical meltdown for Arianna could include tantrums, throwing herself on the floor and general screaming - sometimes getting so violent that she could even physically hurt herself. “I think what prevented the meltdown was that Lauren and Brad were talking to her. They weren’t talking to me, they were talking to her.”
Several minutes later, when the new, unbroken cheeseburger arrived, Arianna stared at it for a few moments before exclaiming, “Oh, I missed you!” and kissing the top of the burger bun.
MacLean quickly snapped a picture and showed it to Wells, jokingly telling her “I think we glorified the cheeseburger a little too much.” Wells, lighting up like a Christmas tree and smiling from ear to ear, asked if she could show the picture to her co-workers and manager.
“It was a cute story. I’ve never heard of a broken cheeseburger, or anything else ‘broken’ for that matter,” said Wells, explaining that she wanted to share it with her coworkers because it was such a sincere interaction.
“It was just a really, really touching experience just to see that kind of compassion and professionalism,” said MacLean. “[Lauren] could have easily just been like, ‘Okay...’ and gone to get her a new one. But she went above and beyond and I feel like everybody involved that was working that day from the hostess to the line cook, just everybody, was super, super amazing. It’s just not something that we’re used to when we have situations like that come up.”
MacLean, who works in customer service for an insurance company and recognizes good service when she sees it, decided to share her story on Chili's Facebook page. The story quickly went viral (it has been shared near 160,000 times and liked by more than 667,000 people) touching hearts around the nation.
MacLean hopes it does more than that, though; she hopes it helps people recognize that not every kid screaming in a restaurant is an uncontrollable brat.
“While we’ve never had a personal experience like this, we know people who have been asked to leave restaurants when their kid with autism starts getting out of hand. It’s so heartbreaking,” said MacLean.
While MacLean and Arianna have never been told to leave a restaurant, they have had experiences where Arianna has gotten too overwhelmed or overstimulated at the table. Other people haven't always understood her autism, and MacLean has chosen on her own accord to leave.
Arianna will sometimes growl while she is eating. MacLean believes that it may be a sensory thing that Arianna chooses to do, or that she may like the feel of growling while she eats her food. Fellow patrons haven't always understood. “We’re used to it and it’s fine, but there were some people sitting next to us and they got up and moved clear across to the other side of the restaurant because it was bothering them so bad.”
The lack of understanding can be frustrating, says MacLean. When Arianna is having a meltdown, most people think she’s just being a brat and that she's being babied. The older sister can't deliver a disclaimer about Arianna’s autism everywhere she goes, but if people are interested she will tell them. The tone of the interaction invariably changes - but words are always directed toward MacLean and never Arianna.
This made Wells' and Cattermole's interactions with Arianna all the more special. “It’s so silly," MacLean said, "but I know every person out there that has a kid with autism can relate. That broken cheeseburger can make or break our day and it made our day, and the rest of the day was great.”
MacLean admitted that she never meant for the Facebook post to go viral; rather, she wanted to recognize Wells and Cattermole for their stellar ability to connect with Arianna on a human level. “It’s not so much that we need to bring autism awareness on a customer service level," she said, "but on a normal, typical social human being interaction. Being sensitive to people whether they have autism or they don’t.”
“I think this stuff happens more often than people recognize,” Cattermole said, “but it was Anna going on to spend 15 minutes to recognize a job well done which led to this outpouring of support.”
Wells agreed, saying that while it was definitely a table she wouldn’t forget, she never expected the response MacLean’s story received. She went on to explain that her interaction with the family didn’t seem weird or out of the ordinary to her.
“It makes me so sad that this is [considered] abnormal,” said Wells. “I was just being myself. I didn’t expect any of this; it’s been overwhelming but definitely cool.”
Chili’s parent company Brinker International Restaurants echoed Cattermole's and Wells’ sentiments in an official statement emailed to CNN.
“Moments like the one from Midvale happen in our restaurants every day, at every table, at every Chili’s across the country. We are delighted by the shining examples in Lauren Wells, Brad Cattermole and the Midvale team, and their kind gestures that made Arianna, Anna and Alex [MacLean's husband] feel so incredibly special. This story made our Midvale team members heroes, and we are so proud to have so many local heroes in our restaurants nationwide who make everyday moments like Arianna’s so heartwarming.”
MacLean has since read the hundreds of comment from strangers on her Facebook post, many of whom admitted they have never thought of something like that when encountering a screaming child at a restaurant. Her hope is that the next time they see a kid being a little different they might just think, "Maybe they have autism; maybe there’s something a little more than meets the eye.”
And for the record, Chili's didn’t charge for the new, “unbroken” cheeseburger.

jueves, mayo 31, 2012

New drugs, fresh hope for autism patients

Image: Nine-year-old Jack Balter plays tug-of-war with his sister Brianna at their home in Scottsdale, Arizona.

Joshua Lott  /  Reuters
Nine-year-old Jack Balter plays tug-of-war with his sister Brianna at their home in Scottsdale, Arizona, on May 17.

msnbc.msn.com/
Lynn and Neil Balter always dreaded stage productions at their son Jack's elementary school.
When Jack was up there with the other performers, the noise, the lights, the crowd almost always got to him, and he would "start spinning," wandering around the stage or turning in circles, Lynn says. "It usually turned into an embarrassing situation," she adds.
But at a dance performance at Jack's Scottsdale, Arizona, school last December, something was different. "He was half a beat behind in the dance, but he did the whole thing," Neil says. "He participated and took the bow with his class."
Afterward, Jack's teacher greeted the Balters in tears. "I don't know what is going on with this kid, but there is this miracle happening and I have a different kid at school," she told the Balters.
Jack, 9 years old, has autism. What his teacher didn't know is that Jack was taking part in a clinical trial for a drug aimed at overcoming some of the social impairment associated with autism, a spectrum of disorders that range from the social awkwardness and narrow interests seen in Asperger syndrome to severe communication and intellectual disabilities.
For years the best that doctors have been able to offer patients with autism is intensive therapy and anti-psychotic drugs such as Johnson & Johnson's Risperdal to blunt some of the extreme behaviors associated with their disorder - tantrums, aggression and self-harm. Anti-psychotics quiet the patients. But they do nothing to address the core social and communication problems that make it impossible for many autistic children to develop deep relationships with their families and peers and grow into independently functioning adults.
As Jack's experience suggests, that may be about to change. Researchers are conducting advanced trials of the first drugs expressly designed to correct the genetically induced signaling problems in the brain that result in autism. The early indications are positive enough to offer new hope for families and spark interest from drug companies.  More >>

sábado, octubre 29, 2011

Autistic boy found alive 6 days after vanishing

An 8-year-old autistic boy was found alive Friday, nearly six days after he wandered away from his family while walking in a wooded park.
Robert Wood Jr. was found in a fetal position in a creek bed at a quarry about 20 miles north of Richmond around 2 p.m., Hanover County Sheriff David Hines said. Wood was in good condition, but was taken to a Richmond hospital where he was reunited with his family.
The boy was found about one mile from North Anna Battlefield Park, where he disappeared while on a walk with family on Sunday.
Wood had been the focus of an intense search attracting more than 1,000 volunteers some days and assisted by professional search-and-rescue teams.

lunes, septiembre 19, 2011

Autism in Another Ape: A baby bonobo suffers autism

Scientific American
By Nina Bai
 
Teco shows more interest in objects than in his family—much as autistic children do. Image: Courtesy of Elizabeth Rubert-Pugh, Great Ape Trust
Rambunctious one-year-old Teco, a third-generation captive-born bonobo at the Great Ape Trust in Des Moines, Iowa, has an ape’s usual fondness for games and grapes. But perhaps because of trauma from a difficult birth (his mother was in labor for 60 hours) or a genetic predisposition, Teco is different from his bonobo peers in ways that resemble autism in young children. He could not cling to his mother or nurse the way healthy young apes do instinctively, mimicking the aversion to physical contact seen in children with autism. Teco also tends to fixate on shiny objects and avoids eye contact, and he has trouble coordinating his four limbs. A genetic analysis of bonobos, already under way, may shed light on Teco’s condition and offer new perspectives on autism’s genetic roots in humans.
Read more >

viernes, abril 01, 2011

Niño autista de 12 años con mayor #IQ que Albert #Einstein

Tan sólo tiene 12 años, pero Jacob Barnet, ya está inscrito en la universidad, este niño prodigio, ha asombrado a los profesores de la universidad de Indiana en Estados Unidos, después de lidiar con algunos conceptos muy avanzados en matemáticas, Jacob tiene un IQ de 170 -- más alto que el de Albert Einstein, y en tan sólo una semana aprendió po si mismo calculo algebra, geometria y trigonometria.
Jacob fue diagnosticado desde muy temprano con el síndrome de Asperger, una forma leve de autismo, aunque sus padres se preocuparon, en aquel entonces, porque su niño todavia no hablaba teniendo 2 años de edad, al paso del tiempo, se dieron cuenta de lo especial que fue su regalo, a los 8 años de edad dejó la secundaria y comenzó la universidad, recibiendo clases de astrofísica.

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Retratos de fusilados por el Castrismo - Juan Abreu

"Hablame"

"EN TIEMPOS DIFÍCILES" - Heberto Padilla

A aquel hombre le pidieron su tiempo

para que lo juntara al tiempo de la Historia.

Le pidieron las manos,

porque para una época difícil

nada hay mejor que un par de buenas manos.

Le pidieron los ojos

que alguna vez tuvieron lágrimas

para que contemplara el lado claro

(especialmente el lado claro de la vida)

porque para el horror basta un ojo de asombro.

Le pidieron sus labios

resecos y cuarteados para afirmar,

para erigir, con cada afirmación, un sueño

(el-alto-sueño);

le pidieron las piernas

duras y nudosas

(sus viejas piernas andariegas),

porque en tiempos difíciles

¿algo hay mejor que un par de piernas

para la construcción o la trinchera?

Le pidieron el bosque que lo nutrió de niño,

con su árbol obediente.

Le pidieron el pecho, el corazón, los hombros.

Le dijeron

que eso era estrictamente necesario.

Le explicaron después

que toda esta donación resultaria inútil.

sin entregar la lengua,

porque en tiempos difíciles

nada es tan útil para atajar el odio o la mentira.

Y finalmente le rogaron

que, por favor, echase a andar,

porque en tiempos difíciles

esta es, sin duda, la prueba decisiva.

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La columna de Cubanalisis

NEOCASTRISMO [Hacer click en la imagen]

NEOCASTRISMO [Hacer click en la imagen]
¨Saturno jugando con sus hijos¨/ Pedro Pablo Oliva

Seguidores

Carta desde la carcel de Fidel Castro Ruz

“…después de todo, para mí la cárcel es un buen descanso, que sólo tiene de malo el que es obligatorio. Leo mucho y estudio mucho. Parece increíble, las horas pasan como si fuesen minutos y yo, que soy de temperamento intranquilo, me paso el día leyendo, apenas sin moverme para nada. La correspondencia llega normalmente…”

“…Como soy cocinero, de vez en cuando me entretengo preparando algún pisto. Hace poco me mandó mi hermana desde Oriente un pequeño jamón y preparé un bisté con jalea de guayaba. También preparo spaghettis de vez en cuando, de distintas formas, inventadas todas por mí; o bien tortilla de queso. ¡Ah! ¡Qué bien me quedan! por supuesto, que el repertorio no se queda ahí. Cuelo también café que me queda muy sabroso”.
“…En cuanto a fumar, en estos días pasados he estado rico: una caja de tabacos H. Upman del doctor Miró Cardona, dos cajas muy buenas de mi hermano Ramón….”.
“Me voy a cenar: spaghettis con calamares, bombones italianos de postre, café acabadito de colar y después un H. Upman #4. ¿No me envidias?”.
“…Me cuidan, me cuidan un poquito entre todos. No le hacen caso a uno, siempre estoy peleando para que no me manden nada. Cuando cojo el sol por la mañana en shorts y siento el aire de mar, me parece que estoy en una playa… ¡Me van a hacer creer que estoy de vacaciones! ¿Qué diría Carlos Marx de semejantes revolucionarios?”.

Quotes

¨La patria es dicha de todos, y dolor de todos, y cielo para todos, y no feudo ni capellaní­a de nadie¨ - Marti

"No temas ni a la prision, ni a la pobreza, ni a la muerte. Teme al miedo"
-
Giacomo Leopardi

¨Por eso es muy importante, Vicky, hijo mío, que recuerdes siempre para qué sirve la cabeza: para atravesar paredes¨Halvar de Flake [El vikingo]

"Como no me he preocupado de nacer, no me preocupo de morir" - Lorca

"Al final, no os preguntarán qué habéis sabido, sino qué habéis hecho" - Jean de Gerson

"Si queremos que todo siga como está, es necesario que todo cambie" - Giuseppe Tomasi di Lampedusa

"Todo hombre paga su grandeza con muchas pequeñeces, su victoria con muchas derrotas, su riqueza con múltiples quiebras" - Giovanni Papini


"Life is what happens while you are busy making other plans" - John Lennon

"Habla bajo, lleva siempre un gran palo y llegarás lejos" - Proverbio Africano

"No hay medicina para el miedo" - Proverbio escoces

"El supremo arte de la guerra es doblegar al enemigo sin luchar"
- Sun Tzu

"You do not really understand something unless you can explain it to your grandmother" - Albert Einstein

"It is inaccurate to say I hate everything. I am strongly in favor of common sense, common honesty, and common decency. This makes me forever ineligible for public office" - H. L. Menken

"I swore never to be silent whenever and wherever human beings endure suffering and humiliation. We must always take sides. Neutrality helps the oppressor, never the victim. Silence encourages the tormentor, never the tormented" - Elie Wiesel

"Stay hungry, stay foolish" -
Steve Jobs

"If you put the federal government in charge of the Sahara Desert , in five years ther'ed be a shortage of sand" - Milton Friedman

"The tragedy of modern man is not that he knows less and less about the meaning of his own life, but that it bothers him less and less" - Vaclav Havel

"No se puede controlar el resultado, pero si lo que uno haga para alcanzarlo" -
Vitor Belfort [MMA Fighter]

Liborio

Liborio
A la puerta de la gloria está San Pedro sentado y ve llegar a su lado a un hombre de cierta historia. No consigue hacer memoria y le pregunta con celo: ¿Quién eras allá en el suelo? Era Liborio mi nombre. Has sufrido mucho, hombre, entra, te has ganado el cielo.

Para Raul Castro

Cuba ocupa el penultimo lugar en el mundo en libertad economica solo superada por Corea del Norte.

Cuba ocupa el lugar 147 entre 153 paises evaluados en "Democracia, Mercado y Transparencia 2007"

Cuando vinieron

Cuando vinieron a buscar a los comunistas, Callé: yo no soy comunista.
Cuando vinieron a buscar a los sindicalistas, Callé: yo no soy sindicalista.
Cuando vinieron a buscar a los judíos, Callé: yo no soy judío. Cuando vinieron a buscar a los católicos, Callé: yo no soy “tan católico”.
Cuando vinieron a buscarme a mí, Callé: no había quien me escuchara.

Reverendo Martin Niemöller

Martha Colmenares

Martha Colmenares
Un sitio donde los hechos y sus huellas nos conmueven o cautivan
Bloggers Unite

CUBA LLORA Y EL MUNDO Y NOSOTROS NO ESCUCHAMOS

Donde esta el Mundo, donde los Democratas, donde los Liberales? El pueblo de Cuba llora y nadie escucha.
Donde estan los Green, los Socialdemocratas, los Ricos y los Pobres, los Con Voz y Sin Voz? Cuba llora y nadie escucha.
Donde estan el Jet Set, los Reyes y Principes, Patricios y Plebeyos? Cuba desesperada clama por solidaridad.
Donde Bob Dylan, donde Martin Luther King, donde Hollywood y sus estrellas? Donde la Middle Class democrata y conservadora, o acaso tambien liberal a ratos? Y Gandhi? Y el Dios de Todos?
Donde los Santos y Virgenes; los Dioses de Cristianos, Protestantes, Musulmanes, Budistas, Testigos de Jehova y Adventistas del Septimo Dia. Donde estan Ochun y todas las deidades del Panteon Yoruba que no acuden a nuestro llanto? Donde Juan Pablo II que no exige mas que Cuba se abra al Mundo y que el Mundo se abra a Cuba?
Que hacen ahora mismo Alberto de Monaco y el Principe Felipe que no los escuchamos? Donde Madonna, donde Angelina Jolie y sus adoptados around de world; o nos hara falta un Brando erguido en un Oscar por Cuba? Donde Sean Penn?
Donde esta la Aristocracia Obrera y los Obreros menos Aristocraticos, donde los Working Class que no estan junto a un pueblo que lanquidece, sufre y llora por la ignominia?
Que hacen ahora mismo Zapatero y Rajoy que no los escuchamos, y Harper y Dion, e Hillary y Obama; donde McCain que no los escuchamos? Y los muertos? Y los que estan muriendo? Y los que van a morir? Y los que se lanzan desesperados al mar?
Donde estan el minero cantabrico o el pescador de percebes gijonese? Los Canarios donde estan? A los africanos no los oimos, y a los australianos con su acento de hombres duros tampoco. Y aquellos chinos milenarios de Canton que fundaron raices eternas en la Isla? Y que de la Queen Elizabeth y los Lords y Gentlemen? Que hace ahora mismo el combativo Principe Harry que no lo escuchamos?
Donde los Rockefellers? Donde los Duponts? Donde Kate Moss? Donde el Presidente de la ONU? Y Solana donde esta? Y los Generales y Doctores? Y los Lam y los Fabelo, y los Sivio y los Fito Paez?
Y que de Canseco y Miñoso? Y de los veteranos de Bahia de Cochinos y de los balseros y de los recien llegados? Y Carlos Otero y Susana Perez? Y el Bola, y Pancho Cespedes? Y YO y TU?
Y todos nosotros que estamos aqui y alla rumiando frustaciones y resquemores, envidias y sinsabores; autoelogios y nostalgias, en tanto Louis Michel comulga con Perez Roque mientras Biscet y una NACION lanquidecen?
Donde Maceo, donde Marti; donde aquel Villena con su carga para matar bribones?
Cuba llora y clama y el Mundo NO ESCUCHA!!!

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