Nano Bubbles: Revolutionary new cancer treatment

itnnews

New genetic clues to 4 types of breast cancer found

NBC/

NEW YORK — Scientists reported Sunday that they have completed a major analysis of the genetics of breast cancer, finding four major classes of the disease. They hope their work will lead to more effective treatments, perhaps with some drugs already in use.

The new finding offers hints that one type of breast cancer might be vulnerable to drugs that already work against ovarian cancer.

The study, published online Sunday by the journal Nature, is the latest example of research into the biological details of tumors, rather than focusing primarily on where cancer arises in the body.

The hope is that such research can reveal cancer's genetic weaknesses for better drug targeting.

"With this study, we're one giant step closer to understanding the genetic origins of the four major subtypes of breast cancer," Dr. Matthew Ellis of the Washington University School of Medicine said in a statement. He is a co-leader of the research.

"Now we can investigate which drugs work best for patients based on the genetic profiles of their tumors," he said.

The researchers analyzed DNA of breast cancer tumors from 825 patients, looking for abnormalities. Altogether, they reported, breast cancers appear to fall into four main classes when viewed in this way.

One class showed similarities to ovarian cancers, suggesting it may be driven by similar biological developments.

"It's clear they are genetically more similar to ovarian tumors than to other breast cancers," Ellis said. "Whether they can be treated the same way is an intriguing possibility that needs to be explored."

The report is the latest from the Cancer Genome Atlas, a federally funded project that has produced similar analyses for brain, colorectal, lung, and ovarian cancers.

Lance Armstrong runs in Montreal

GlobalToronto

Donna Summer dead at 63

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Jerusalem hospital shows off vaccine that destroys cancer in 2 shots.

Yourjewishnews.com

Hadassah Medical Centre in Jerusalem

Early human test results suggest a vaccine can train cancer patients' bodies to seek out and destroy tumour cells.
The therapy, which targets a molecule found in 90 per cent of cancers, eventually could provide an injection that would allow patients' immune systems to fight off common cancers including breast and prostate cancer.
The first results of trials in people, at the Hadassah Medical Centre in Jerusalem, suggest the vaccine can reduce levels of disease. The human work is so preliminary it has yet to be published in a scientific journal.
The scientists behind the vaccine hope to conduct more extensive trials to prove it can be effective against a range of cancers. They believe it could be used to fight small tumours if they are detected early or to help prevent the return and spread of disease in patients who have undergone conventional treatment.
In the safety trial at Hadassah, 10 patients with multiple myeloma, a blood cancer, received the vaccine. Seven have finished the treatment and the developer, drug company Vaxil Biotherapeutics, reported all had greater immunity against cancer cells compared with before they were given the vaccine. Vaxil added that three patients were free of detectable cancer following the treatment.
Cancer cells usually evade a patient's immune system because they are not recognized as a threat. While the immune system usually attacks foreign cells such as bacteria, tumours are formed of the patient's own cells that have malfunctioned.
Scientists have discovered that a molecule called MUC1, which is found on the surface of cancer cells, can be used to help the immune sys-tem detect tumours. The new vaccine, ImMucin, developed by Vaxil and researchers at Tel Aviv University, uses a section of the molecule to prime the immune system so it can identify and thus destroy cancer cells. 

Vaxil suggested that if large-scale trials prove as successful, the vaccine could be available within six years. Initial research on the vaccine, in mice, was published in the journal Vaccine, and suggested the treatment induced "potent" immunity in mice and increased their survival from cancer.
Cancer charities gave the vaccine a cautious welcome. Dr. Kat Arney, at Cancer Research UK, said: "These are very early results that are yet to be fully published, so there's a lot more work to be done to prove that this particular vaccine is safe and effective in cancer patients."

Can blueberries benefit your health?

A tearful Chavez breaks down: 'Jesus ... do not take me yet'

 Read >>

Chávez regresará a Cuba para recibir tratamiento

BBC Mundo
Chávez dijo estar seguro de que la "gran mayoría" de los venezolanos lo apoyará en su decisión de volver a Cuba. Radioterapia "como complemento" a la cirugía de hace un mes, cuando le extirparon un segundo tumor canceroso. "Esta noche salgo hacia La Habana ...   Mas >>

La saga del cancer de Chavez: "Tiene un tumor con tres metástasis"

ABC.es

El doctor José Rafael Marquina, médico internista venezolano, especializado en cuidados intensivos, de los pulmones y sueño, residente en Florida, y profesor de la Nova University, concede una amplia entrevista telefónica a ABC sobre la enfermedad del presidente Hugo Chávez, cuyos informes obtiene de primera mano con lujo de detalles.

-¿Tras su regreso de La Habana, cuál es el tratamiento que le darán a Chávez en Caracas?

-Le aplicarán unas 30 sesiones de radioterapia y no 25 como se había pensado. En Caracas ya empezó el tratamiento en el Hospital Militar.

-¿Cuántas sesiones se hicieron en Cuba? ¿Dieron algún resultado?

-En Cuba le dieron 10 sesiones y Chávez no ha respondido al tratamiento. El problema en el centro médico cubano es que se lo aplicaron de forma desorganizada. Se lo suspendieron cuando le visitó el presidente colombiano Santos. Fue un desastre. Al presidente le estaban dando la radiación sin tatuaje.

-¿Qué significa eso?

-Hay que marcar la zona donde se va a dar la radiación. Los médicos cubanos empezaron sin tatuarlo, decían que no lo necesitaba. Levantaban al presidente a las 6 de la mañana, lo llevaban al primer piso del centro médico CIMEQ, le hacían la tomografía computarizada y luego la radio. El médico brasileño les recomendó el tatuaje cuando le examinó el jueves 15.

-¿Cuánta radiación le dieron en Cuba?

-En Cuba le han dado 5.000 “rads” por dosis y por área. En Caracas no sé cuánto, todo es un misterio con la radioterapia y no han querido dar información.

-¿Cuál fue el resultado de la biopsia que le sacaron en Cuba?

-No conozco los resultados de la biopsia. Las láminas la mandaron a los EE.UU. y Brasil. Los cubanos asumen que tenía células malignas, cancerígenas.

-¿Finalmente no se operó en Cuba como afirma el norteamericano Roger Noriega o fue una intervención superficial con laparoscopia como dice usted?

-Primero hay que aclarar que Chávez tiene un tumor cancerígeno que ha hecho tres metástasis: en el hígado, en las glándulas suprarrenales y en el área retropiroteneal y la vejiga. Después de que me llamaran para decirme que tenía un nuevo tumor de dos centímetros y que había que operarlo en Caracas, Chávez prefirió hacerlo en La Habana, donde le practicaron la laparoscopia. Ahí vieron lo avanzado del cáncer y decidieron sólo limpiarle los bordes necróticos.  Mas >>

Visiblemente deteriorado Lula da Silva

Lula recibe la visita del senador Eduardo Braga en el hospital Sirio-Libanes de Sao Paulo

Hugo Chavez Says Tumor Extracted in Cuba Was Cancerous

CARACAS, Venezuela (AP) — Venezuelan President Hugo Chavez revealed Sunday that a new tumor recently removed from his pelvic region was of the same type of cancer as a baseball-sized growth extracted from that part of his body about eight months ago.

In his first TV appearance in nine days, Chavez said the surgery and follow-up tests showed the tumor was "a recurrence of the initially diagnosed cancer."

He said the tumor was totally extracted and noted "the absence of lesions suggestive of cancer neither locally, neither in nearby organs, neither far away ... neither metastasis, none of this thanks to God, to the diagnosis and rapid intervention."

The 57-year-old president said he would spend several weeks recovering and then "we are going to do radiation treatment in the area ... without discarding other treatment options."

"There isn't fever nor any other sign, neither infection, hemorrhage," he said. He called the post-surgery healing "perfect in relation to the time that's passed, and we are already doing physical therapy."

Chavez spoke firmly in footage recorded Saturday in Havana while accompanied by various government ministers and older brother Adan Chavez. The president said his recuperation has been "open, progressive and rapid" in the footage aired Sunday in Venezuela.

Chavez said "still it hasn't been six days because the operation ended on the night of last Sunday." He verified the date of the recording by displaying a Saturday copy of the Cuban government newspaper Granma and a similar copy of the Venezuelan government paper Correo del Orinoco.

"We are very optimistic," he said while seated at an oval conference table. "There is a very favorable medical evolution, the vital signs very favorable."

Chavez underwent several weeks of radiation treatment in 2011.

Chavez flew to Cuba for his most recent surgery on Feb. 24, and his absence from the public spotlight since then has sparked speculation about his health. Chavez did phone into a show Friday on Venezuelan state television when he said he was recovering well.

Chavez hasn't specified what kind of cancer he has or exactly where it's located. But cancer specialists say that based on available information, Chavez appears to suffer from a relatively rare cancer known as sarcoma, which tends to reappear in the same location where related tumors are removed.

The president has taken pains to demonstrate unflagging energy in his public appearances as he faces a tough re-election battle this November.

"Everyone who has been operated on knows ... the impact of an operation of various hours," Chavez said in the most recent footage. "And how, above all the first day when the body begins to awaken, the pains begin, the obstacles, after one goes step by step recovering the functions of the body, like I'm recovering."

He added, "Since almost the second day, I began to walk. For this, I say thanks to God, to everybody."

He spoke in a stark, white-walled room, in front of paintings of Cuban independence leader Jose Marti and South American hero Simon Bolivar. With no one taking over his duties in Venezuela, Chavez issued instructions to government ministers and approved the budgets of various state-owned companies.

As he has done in recent weeks, Chavez defended Syrian President Bashar Al-Assad, who has tried to violently crush a popular revolt in much of the Middle Eastern country. Venezuela has at least twice sent shipments of diesel oil to Syria over the past months.

"We continue lamenting the aggressions against Syria," Chavez said, "and the pressure of the United States government and many European countries, failing to recognize the sovereignty of a people such as the Syrian people."

"From here," Chavez said, "we send our solidarity to the Syrian people and to President Bashar Al-Assad."

Later Sunday, at Havana's cathedral, a service was held for Chavez's health.

Chavez is "in good spirts and boosted by the support and love of the Venezuelan people," said Venezuelan Foreign Minister Nicolas Maduro, who was at the service.

In Venezuela, Chavez supporter Johsny Flores said his faith in the leader remains high despite the reports of ill health.

"Cancer is a serious illness, but I know that Chavez has so much love for the country, so much desire to continue with us, that he has going to come out of this," said Flores, a 35-year-old street vendor.

On the other side of the political fence, merchant Tomas Gutierrez followed the example of sole opposition presidential candidate Henrique Capriles and wished Chavez a swift recovery even as he longed for an end to the leader's 13-year rule.

"Another person in his place would be on the floor," the 63-year-old said. "We have to recognize his will power. But also, we hope that he gets better and that Capriles wins and puts an end to this disastrous government."

Crucial medicine to treat childhood leukemia is in such short supply

By GARDINER HARRIS

A crucial medicine to treat childhood leukemia is in such short supply that hospitals across the country may exhaust their stores within the next two weeks, leaving hundreds and perhaps thousands of children at risk of dying from a largely curable disease, federal officials and cancer doctors say.

“This is dire,” said Valerie Jensen, associate director of the Food and Drug Administration’s drug shortages program. “Supplies are just not meeting demand.”

The drug is methotrexate, and the cancer it treats is known as acute lymphoblastic leukemia, or A.L.L., which most often strikes children ages 2 to 5.

It is an unusually virulent cancer of white blood cells that are overproduced in bone marrow and invade other parts of the body.

The cancer commonly spreads to the lining of the spine and brain, and oncologists prevent this by injecting large quantities of preservative-free methotrexate directly into the spinal fluid.

The preservative can cause paralysis when injected into the spinal column, so cannot be used for this disease. Methotrexate is also used to treat rheumatoid arthritis.

Quality concerns Ben Venue Laboratories was one of the nation’s largest suppliers of injectable preservative-free methotrexate, but the company voluntarily suspended operations at its plant in Bedford, Ohio, in November because of “significant manufacturing and quality concerns,” the company announced.

Since then, supplies of methotrexate have gradually dwindled to the point where oncologists now say they are fearful that shortfalls may occur at many hospitals within two weeks.

“This is a crisis that I hope the F.D.A.’s hard work can help to avert,” said Dr. Michael P. Link, president of the American Society of Clinical Oncology. “We have worked very hard to take what was an incurable disease and make it curable for 90 percent of the cases. But if we can’t get this drug anymore, that sets us back decades.” More >>

Lula y Lugo en un hospital de Sao Paolo

yahoo news/

Lula que tiene tambien su Instituto >>

mTor: A New Path to Longevity

Scientific American/

In 2009 scientists discovered that a drug called rapamycin could significantly extend life span in mice, doing so by interfering with the activity of a protein called mammalian TOR, or mTOR.
The finding is the most compelling evidence to date that mammalian aging can be slowed pharmaceutically, and it galvanized interest in mTOR’s role in the aging process.
The result also highlighted a mystery: Why would suppressing cellular growth and replication—oneeffect of interfering with mTOR—extend life span?
Research into that question could lead to medicines that postpone or mitigate aging-related disorders—from Alzheimer’s disease to cancer to heart failure—and perhaps even extend how long humans can live.

Correo - Panegirico u obituario a Lula

El Granma se baja hoy con un  panegirico sobre Lula con un fuerte olor a incienzo funerario y recuerda que   "El cáncer parece perseguir a los jefes de Estado: Lugo, Chávez, José Alencar,...", en lo que es la primera interrogante publica castrista sobre la superacion de la enfermedad por parte de Chavez. 

Fotos: Lula a su llegada al Hospital Sirio- Libanés de São Paulo, reconocida institucion con rango mundial. 

Pronostico de médico del hospital sobre el cancer que padece Lula 

Are Cuban Doctors Killing Chavez?

Capitol Hill Cubans

 

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Tributo a Elena Tamargo (1957-2011†)

 

Foto tomada de Project Zu

Poemas de Elena Tamargo tomados de  "Poemas de"

 Compás De Espera

Mi pasado está invadido

y lloro lentamente.

Me ha llenado de miedo una noche en el Neva

me ha llenado de fe una tarde en Bakú.

Se quedó Samarcanda como alguna promesa

y la calle de Arbat para soñar a Eszenin

siempre, siempre.

Erré como torcaz

aplastada en la calle por un caballo ciego.

Me dan miedo mi pueblo y sus hombres

mientras Jesús del Monte se derrumba en silencio.

Una ciudad de espejos y banderas

y su empinada ronda de tenores.

Yo regreso a mis pájaros

al pequeño amarillo que no canta.

Ya no tengo balcón ni noches junto al mar

  y otra campana traza mis compases de espera.

Estorbo como estorban los almendros

y en el farol se queman algunas mariposas.

Ciudad y almendro y yo

ay, qué desgracia.

 Fragmentos De La Habana

Pensar, robar, gozar
todo un único espasmo.
Arpegia y pica, Lázaro.
Salta de los tejados cuando nadie te vea
y muestra el interior de la sonata.
Aquella criatura desenfrenó la nada.
Es la maldad tan natural lo que te bambolea.
Veo tu insomnio a su manera
veo el disco girar y a los hombres
veo charcos, tranvías
veo enormes pedazos de La Habana.
A los negros los veo
resonando a sus pies el toque de los siglos.
Negros espirituales.
Blanco el mantel del primer desayuno
blanco mi abuelo
blancos en el exilio, desconcertados
borrachos de blancura
blancos los hospitales
negro mi cuerpo en el primer amor.
Llegan las mariposas a confirmar que ardí
y me dejan besando su jadeo
la inútil ceremonia
junto al candil oscuro.

 Habana Tú

Y hoy está crecido el mar
no es que la marea suba por un hecho natural
es que llora Yemayá
Juan Formell

De niña, entre las grietas de la tierra

buscaba en ti mi aurora

a semejanza mía, a semejanza tuya

cuerpo oscuro y esbelto de mi sueño.

Puras ante la espera las imágenes

emisarias de la tarde que caía

pegada a su horizonte.

Tenías en secreto tu espigón de metales

inclinada en tu borde busco el ancla perdida

te busco en el regreso, estás llena de pájaros

vuelve a secar tus manos y cuéntamelo todo.

Era esto el abandono y lo sabías.

Óyeme estos lamentos que me salen ardiendo

  yo sólo te deseo,

la sombra de aquel tiempo en ti misma entrevista

con inútil ternura

y tú me dabas fuerza

rendida y dócil como el mar sabe serlo.

Aquel concilio que tantos han cantado

sin una urgencia propia como ésta de este instante.

Tampoco fue tu culpa si no les comprendiste la amargura

faltándoles la leche y el abrigo

  te lo dieron todo, vida que no pedías.

Habanera Yo

Soy otra vez muchacha en el invierno
y nadie me regala una gardenia.
Pero el regreso de mis lunas
ahíjo taciturna del fondo de la calle
  casi feliz, aletargada
bajo esta piedra roja.
Retozo como un campo florecido
es la herencia adecuada de una mujer despierta
un sueño desprendido del cuerpo que lo ha usado.
Los lirios de Rosita
mis únicos testigos
esperan la lechuza
en el silencio mío del oeste.
Vuelvo en la medianoche de este invierno
acércate a escuchar mi tambor y mi oboe
acércate con riesgo de hechizarme.
Ciudad, ciudad
no mates mi manía de ser bella
de pasearme desnuda y cepillarme el pelo.
Ciudad con pajaritos y cisternas
el probable lugar donde acabó una historia.
Ay, mi ciudad
  mi pasto
mi sitio recurrente
a la hora en que duermen las palomas.
Ciudad que has bendecido mis vigilias
arrástrame hacia el mar
sin farolas ni víctimas
con algas en mi pelo
y en tu pelo de sal.

 Mar De Mi Patio

Y si llegaras mar
cuando mi cuerpo fuera tierra arada
y lloviera en mis ojos?
Alga y sal de prusia calentura
¿no te crecen las uñas?
Te veré frente a frente
presa en tus quemaduras, levantando las cejas
dejando ver los ojos con esa indiferencia.
Cómo tú eras cuando yo te elegí.
Diosa naciendo y destronando diosas
si tú al verme fijaras la mirada.
Ven hacia mí, no tardes
puedo perder las fuerzas.
Estoy sola bailando y en mi musgo
me pisan miles de pies desesperados.
Sácame este mareo
este jilguero tosco que custodia mi blanco
esta brújula adivinando el este.
Si te demoras se deshace mi estatua
este cuerpo que danza maravillosamente.
–¿Qué hora es que no llegas
perfumando las calles con tus pescados frescos?–
Mar de mi patio, mar atormentado
lo que me duele
es que mis días
se vuelvan más y más de tierra.

Sincopada O Fuera De Tiempo

Todos los días se matan en La Habana
dos millones de gatos y quinientos caballos.
Quinientas yeguas solas sostienen el rencor de su dureza
se abrazan
en la pira arrogante del león babilónico.
Trasgos de sangre suspenden el azul y el animal del trópico
se agota.
Diez millones de vacas ya murieron
tres mil palomas agonizan
y el olor de los lirios se deslíe
en un prurito de ácidas hormigas.
Los ciudadanos temblando se repliegan
a construir el escenario de la nada
si no quedan caballos ni lengua ni jazmines
si los trenes de leche detuvieron su paso
donde cantaa la belleza
y ahora se escuchan los terribles quejidos de las vacas
si los lirios, los gatos, las palomas
son animales muertos.
Pero yo no he venido a ver el cielo
cómo voy a ordenar pedazos de paisajes
ordenar los amores que son fotografías
y luego tambor tosco, bocanada de sangre.
Ay, voz lejana
ay, voz de la sordera
estás aquí bebiendo mi humor de niña muerta
quiero llorar mi talco, como lloran las niñas
porque yo no soy ni mujer ni poeta ni azucena
soy el agua y el vino y el aceite
una llaga tal vez que debe al fuego
y me andan buscando.

 

La salud de Hugo Chávez segun Roger Noriega

Uploaded by 72pantalla1

Correo- Lula da Silva se anticipa a la quimioterapia y se afeita

globo.com

Cancer Found in 2000-Year-Old Mummy

Discovery

"It is the oldest known case of prostate cancer in ancient Egypt and the‭ ‬second‭ ‬oldest case in history,‭" ‬Prates said.

The earliest diagnosis of‭ ‬metastasizing prostate carcinoma came in‭ ‬2007,‭ ‬when researchers investigated the skeleton of a‭ ‬2,700-year-old Scythian king who died,‭ ‬aged‭ ‬40-50,‭ ‬in the steppe of Southern Siberia,‭ ‬Russia.

‭

"This study shows that cancer did exist in antiquity,‭ ‬for sure in ancient Egypt.‭ ‬The main reason for the scarcity of examples found today might be the lower prevalence of carcinogens and the shorter life expectancy,‭" ‬Paula Veiga,‭ ‬a researcher in Egyptology,‭ ‬told Discovery News.

Moreover,‭ ‬high-resolution CT scanners,‭ ‬able to detect tiny‭ ‬tumors‭ (‬measuring‭ ‬0.03-0.07‭ ‬inches in diameter‭)‬,‭ ‬became available only in‭ ‬2005.‭ ‬This suggests that earlier researchers might have missed several cases.

‭

"This technology improved significantly the interpretation of data.‭ ‬Radiology,‭ ‬and its latest developments,‭ ‬like high resolution CT scan,‭ ‬is a phenomenal non-destructive tool in many fields of art and archeology,‭"‬ Prates said.

More >